The area around Ameno features numerous places of interest in terms of nature and landscapes.

The village nestles in the hills between Lake Orta and Lake Maggiore. A short distance away is Orta San Giulio, the medieval town after which the lake is named, with its island dominated by the Romanesque church of the old convent.
On the opposite side are the Borromeo Islands of Lake Maggiore, as well as the small towns around Stresa in the Borromeo Gulf, and the majestic villas of Verbania.

The residential settlements of the area are particularly beautiful and distinctive, with ancient structures, cobbled lanes, small squares, rural architecture, Baroque, nineteenth century courtyards and palaces.

The Vergante hills, covered in chestnut, beech, pine and birch trees, are threaded with footpaths, bridleways and mountain bike trails. There are also many waterways carved out by rivers, most importantly the River Agogna, which originates on Mottarone and, having run through the Novara and Pavia plains, flows into the River Po.

Crossing the bridge over the Agogna we reach the Cascine (farmsteads) and the surrounding wilderness. On the valley floor is Pezzasco, with its distinctive Roman bridge. Climbing up the wooded hill we reach the uninhabited hamlets of Tacchino and Sculera or, following the main road, Milanetto, Tabarino, Barozzera, Cassano and Pecorino, from which we can continue up towards Monte Barro. Alternatively, we can take the Novara trail after Cassano to the Cappella del Vago shrine and even on to the Alpe Verdina or Alpe Cascinone.